What is the most contagious infection in humans? |
Contagiousness, or transmissibility, of an infectious disease is typically quantified by the basic reproduction number (R₀). Based on epidemiological evidence, measles is the most... |
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What are the cardiovascular benefits of SGLT2 inhibitors for patients with T2DM and CKD? |
SGLT2 inhibitors provide substantial cardiovascular benefits in patients with T2DM and CKD, including reductions in cardiovascular mortality, HF hospitalizations, improvements in... |
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How to differentiate papulopustular rosacea from acne, and how to assess rosacea severity? |
The absence of comedones, presence of persistent erythema, telangiectasia, and ocular involvement strongly favor a diagnosis of rosacea... |
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Are mineralocorticoid and androgen replacements necessary along with glucocorticoids in primary adrenal insufficiency? |
Mineralocorticoid replacement therapy is essential in all patients with confirmed aldosterone deficiency, while DHEA supplementation is not universally necessary but may be beneficial... |
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Is antiseizure prophylaxis necessary for patients with brain metastasis undergoing radiation therapy? |
Antiseizure prophylaxis is not routinely recommended for patients with brain metastasis undergoing radiation therapy, as the risk... |
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When is a CXR indicated in patients with a working diagnosis of acute bronchitis? |
A CXR is indicated in patients with a working diagnosis of acute bronchitis when there is suspicion of pneumonia or other serious conditions, particularly in the presence of severe... |
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What considerations and precautions should be taken before prescribing gabapentin for chronic pelvic pain in women? |
Prescribing gabapentin for chronic pelvic pain in women requires a comprehensive evaluation, consideration of alternative treatments, and careful monitoring for adverse effects such as... |
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What is the evidence for theta-burst stimulation in treatment-resistant depression? |
Current evidence supports the efficacy, safety, and tolerability of theta-burst stimulation, particularly intermittent TBS, in the treatment of treatment-resistant depression... |
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