Traditionally, prolonged intravenous (IV) antibiotic therapy has been the cornerstone of treatment for infective endocarditis (IE). However, recent evidence challenges this paradigm, suggesting that early transition from IV to oral antibiotics may be safe... |
Intrauterine device (IUD) insertion is a widely used method of long-acting reversible contraception, but insertion-related pain remains a significant barrier to broader acceptance and use, especially among nulliparous women and those with increased... |
Physical restraints have historically been employed in critical care settings to ensure patient safety, prevent self-harm, and protect essential medical devices. However, contemporary critical care practice emphasizes minimizing restraint use due to... |
Intra-articular (IA) injection therapies are important adjunctive treatments for knee OA aimed at reducing pain, improving function, and potentially modifying disease progression. Current clinical guidelines recommend several IA injection options... |
A 64-year-old man presents for follow-up of recurrent gout flares. He has experienced three flares over the past 6 months, most recently affecting the left ankle. His current medications include allopurinol 100 mg/day and colchicine PRN during flares. He reports occasional joint swelling between attacks. His most recent serum uric acid level was 7.8 mg/dL... |
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ESO — Intracerebral hemorrhage
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AGA — Ehlers-Danlos syndrome
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DC — Diabetic nephropathy
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ACOG — In-office procedural pain
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ASCRS — Appendiceal neoplasm
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OPTPRESS — High MAP for septic shock in elderly
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PREDMETH — MTX for pulmonary sarcoidosis
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VERITAS — Nav bronchoscopy for lung nodules
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BedMed — Bedtime administration of BP drugs
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A 66-year-old woman with a history of primary open-angle glaucoma presents for follow-up. She has been using a combination of latanoprost, timolol, brimonidine, and dorzolamide for IOP control. Despite adherence to therapy, her IOP remains elevated at 28 mmHg in the right eye and 26 mmHg in the left eye. Visual field testing shows progressive peripheral field loss in both eyes, more pronounced on the right. Optic nerve imaging reveals worsening cupping compared to prior scans.
What is the most appropriate next step in management? - Add oral acetazolamide
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Switch prostaglandin analog to a different class of topical agent
- Initiate neuroprotective agents
- Refer for glaucoma surgery
- Continue current regimen and monitor more closely
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